Dizon, Melissa N. and Exconde, Antolyn E. Jr. (2010) Antimicrobial activity of Artocarpus heterophylla and Musa sapientum crude extracts against methicillin- resistant Staphylococcus aureus. Undergraduate thesis, De La Salle University - Dasmariñas.

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Abstract

The inhibitory activity of Artocarpus heterophylla and Musa sapientum against methicillin-resistant Staphylococcus aureus (MRSA) was observed. The crude extracts gathered from its leaves, roots and fruit were obtained using rotary evaporator. For the antimicrobial assay, the disc diffusion method was used to evaluate the resistance and sensitivity of MRSA based on its zones of inhibition. The results showed that different treatments yielded different values on their mean zones of inhibition. As compared to vancomycin (control group), zones which were 9mm and below were considered to be resistant, while 12mm and above meant that the treatment was an effective antimicrobial against it. Based on the statistical treatment used (Fishers Exact Test), it proved that there was a significant difference between the plants. Artocarpus heterophylla showed an average of 9.72 mm and demonstrated three zones of inhibition that was considered being sensitive while Musa sapientum showed an average of 6.83, showing no sensitivity to the bacteria. The computed p-value with 0.006 was less than expected p-value (p<0.05). When compared to Vancomycin, which yielded the greatest value with 17.00 mm, the sensitivity of MRSA to the data obtained from the different extracts illustrated a minimal inhibitory effect. Therefore, the researchers now conclude that Artocarpus heterophylla and Musa sapientum are not considered as a good antimicrobial for MRSA.

Item Type:	Thesis (Undergraduate)
Additional Information:	CALL NUMBER : BIO 1096 2010
Keywords:	Antimicrobial activity.
Subjects:	Q Science > QH Natural history > QH301 Biology Q Science > QL Zoology
Users:	College of Science and Computer Studies > Biological Science
Depositing User:	Ivyjoy Viray
Date Deposited:	01 Dec 2015 02:43
Last Modified:	15 Oct 2024 02:51
URI:	https://thesis.dlsud.edu.ph/id/eprint/954

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