Effects of potato (Solanum tuberosum) crude glycoalkaloids on the fertility of female albino rats.

Alcedo, Manel Angelica C. and Ramos, Genie Anne P. (2010) Effects of potato (Solanum tuberosum) crude glycoalkaloids on the fertility of female albino rats. Undergraduate thesis, De La Salle University - Dasmariñas.

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Abstract

Treatment of crude potato glycoalkaloids has an effect on the fertility of female albino rats. It affects the normal estrous cycle of rats and results to changes in the duration of cycles. However, there was no difference between the pre- and post-treated rats in terms of frequency of stages except for metestrus. Hence, the observed changes are not dose-dependent. The treatment also induced a decrease in the number of implantation sites within the uterus, an indication of its decreased fecundity. In the histopathology of the ovaries and uterus, the treatment induced a prevalence of basal endometrium; a decrease in the number of corpus luteum and healthy follicles; and an increase in the number of inclusion cysts. These are all indicators of disrupted normal ovarian activity and hormonal synthesis of estrogen and progesterone. Thus, treatment of crude potato glycoalkaloid has a possible anti-fertility effect on female albino rats. 5.2 Recommendations The researchers would like to recommend the following: 1. A further study on the effect of potato glycoalkaloids in the reproductive aspect particularly in the fertility of female rats, with focus on the biochemical and hormonal mechanism of the extract. 46 2. The use of pure glycoalkaloids specifically a-solanine and a-chaconine for a more definite effect. 3. A further investigation on the effect of glycoalkaloids on the fertility of male rats . 4. A study on the possible abortifacient activity of glycoalkaloids.

Item Type: Thesis (Undergraduate)
Additional Information: CALL NUMBER : BIO 1105 2010
Keywords: 1. Solanum tuberosum
Subjects: Q Science > QH Natural history > QH301 Biology
Q Science > QK Botany
Q Science > QL Zoology
Users: College of Science and Computer Studies > Biological Science
Depositing User: Ivyjoy Viray
Date Deposited: 01 Dec 2015 01:30
Last Modified: 01 Dec 2015 01:30
URI: http://thesis.dlsud.edu.ph/id/eprint/930

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