Hepatoprotective effects of L-Ornithine-L-Aspartate during thiazolidinedione treatment of diabetic male albino rats.

Beltran, Ruby May Z. and Tayco, Joan Marie D. (2011) Hepatoprotective effects of L-Ornithine-L-Aspartate during thiazolidinedione treatment of diabetic male albino rats. Undergraduate thesis, De La Salle University - Dasmariñas.

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Abstract

L-Ornithine-L-Aspartate (a hepatoprotective drug) was not able to exert its hepatoprotective effects to prevent the negative effects of Thiazolidinedione (antidiabetic drug). The study was conducted to determine the effects of L-Ornithine- L-Aspartate in Thiazolidine-induced hepatotoxicity. Diabetes was induced to the sixty (60) male albino rats. After being diabetic, different levels L-Ornithine-LAspartate was administered followed by Thiazolidinedione. To check the liver damage, bilirubin and urobilinogen were measured through urinalysis. Different dosage levels of the hepatoprotective drug used did not have any effect in liver damage. The levels of urobnilinogen had a significant difference in the treatment groups.

Item Type: Thesis (Undergraduate)
Additional Information: CALL NUMBER : BIO 1139 2011
Keywords: Hepatoprotective effects ; Thiazolidinedione treatment
Subjects: Q Science > QH Natural history > QH301 Biology
Q Science > QL Zoology
Users: College of Science and Computer Studies > Biological Science
Depositing User: Ivyjoy Viray
Date Deposited: 25 Nov 2015 06:05
Last Modified: 25 Nov 2015 06:05
URI: http://thesis.dlsud.edu.ph/id/eprint/817

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