A comparative study on the angiogenic effects of the crudeshoot extract of artemesia dracunculus L. (Tarragon) and Nepeta cataria L. (Catnip) on the chorioallantoic membrane of a 10 day-old-chick embryo.

Gopez, Fijie Ann A. and Madrid, Kent Aviar F. (2012) A comparative study on the angiogenic effects of the crudeshoot extract of artemesia dracunculus L. (Tarragon) and Nepeta cataria L. (Catnip) on the chorioallantoic membrane of a 10 day-old-chick embryo. Undergraduate thesis, De La Salle University-Dasmariñas.

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Abstract

Angiogenesis is a medical technique used to determine the effect of various plant extracts in the growth of new blood vessels from pre-existing ones. It is used as a pre-test for the foundation of novel drugs that could treat numerous diseases such as cancer and diabetes. In this study, two plant samples were used to test their angiogenic capacity and compare their effects on the chorioallantoic membrane of a 10 day-old chick embryo. 200 grams of the samples, A. dracunculus (tarragon) and N. cataria (catnip) were soaked in 75% ethanol while the extracts were collected using the rotary evaporator. Increasing concentrations of each extract were made (75 ppt, 150 ppt and 300 ppt) and administered onto the chorioallantoic membrane (CAM) of a 10 day old chick embryo. After 48 hours, the CAM of each test egg was harvested and the collaterals were then counted and compared. The results were compared to the control group and it showed that both plants were able to inhibit angiogenesis due to the drastic decrease in the collaterals of the test eggs. Finally, based on the statistical analysis, it was found that N. cataria is a much more favorable angiogenic inhibitor than A. dracunculus due to its inhibitory capacity brought about by its specific chemical component not found in A. dracunculus.

Item Type: Thesis (Undergraduate)
Additional Information: BIO 1194 2012
Keywords: Plant extracts ; Tarragon ; Catnip
Subjects: Q Science > QH Natural history > QH301 Biology
Q Science > QK Botany
Q Science > QL Zoology
Users: College of Science and Computer Studies > Biological Science
Depositing User: Ivyjoy Viray
Date Deposited: 12 Nov 2015 01:29
Last Modified: 12 Nov 2015 01:33
URI: http://thesis.dlsud.edu.ph/id/eprint/475

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