Effects of polyphenol-containing crude extracts of ipomea batatas(L.) Lam.and Basella rubra Linn. To the estradiol valerate-induced polycysticovarian syndrome in albino rats.

Guerrero, Victor J and Sagala, Rec Rellieson V. (2013) Effects of polyphenol-containing crude extracts of ipomea batatas(L.) Lam.and Basella rubra Linn. To the estradiol valerate-induced polycysticovarian syndrome in albino rats. Undergraduate thesis, De La Salle University-Dasmariñas.

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Abstract

This paper is intended to discover the potentials of polyphenols from Ipomoea batatas and Basella rubra extracts against the estradiol valerate (EV) – induced polycystic ovarian syndrome (PCOS) in albino rats. Thirty-six (36) albino rats were divided into nine groups: T1 and T2 were treated with 100 and 500 mg/kg Ipomoea batatas extracts, respectively; T3 and T4 with 100 and 500 mg/kg Basella rubra extracts, respectively; T5 and T6 with 100 and 500 mg/kg combined extracts, respectively; and the control groups: C0, is the normal group; C-, receiving no treatment; and C+, which received 50mg/kg metformin HCl. After the treatment period, the different concentration levels of Ipomoea batatas extract, Basella rubra extract and combined plant extracts showed their ability to normalize the estrous cycle and the prolonged estrus stage of the induced subjects. The elimination of follicular cysts was noticed in all treatment groups except for T3 and T5. Presence of many healthy follicles was also observed in all treatment groups. The present study indicated that polyphenol-containing crude extracts of Basella rubra and Ipomoea batatas have potential efficacy in the prevention and maintenance of PCOS. Further studies regarding their therapeutic effects against PCOS should be carried out to prove their therapeutic potential.

Item Type: Thesis (Undergraduate)
Additional Information: BIO 1223 2013
Keywords: Polyphenol ; Basella rubra ; Ipomoea batatas
Subjects: Q Science > QH Natural history > QH301 Biology
Q Science > QK Botany
Q Science > QL Zoology
Users: College of Science and Computer Studies > Biological Science
Depositing User: Ivyjoy Viray
Date Deposited: 11 Nov 2015 00:32
Last Modified: 11 Nov 2015 00:37
URI: http://thesis.dlsud.edu.ph/id/eprint/423

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