Effect of different leaf concentrations of Rosmarinus officinalis L. (rosemary) in the blood cholesterol level of Albino rattus norvegicus (albino rats).

Gamez, Maria Carmela Fatima C. and Tanael, Nicole T. (2013) Effect of different leaf concentrations of Rosmarinus officinalis L. (rosemary) in the blood cholesterol level of Albino rattus norvegicus (albino rats). Other thesis, De La Salle University-Dasmariñas.

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Abstract

The crude extract of Rosmarinus officinalis L. (Rosemary) was tested on its effect on the cholesterol activity of albino rats. Hypercholesterolemia was induced to the albino rats by high-fat diet using buttered pellets. Normal baseline blood was collected prior to the administration of 50%, 75% and 100% extract of rosemary leaves. The study showed that the various concentration of extracted rosemary has a significant effect in lowering the blood cholesterol level of the albino rats. Best concentrations were also determined before treatment. The concentrations 75% and 100% were given to treatments as once daily and twice daily. Weekly monitoring of blood cholesterol was done for ten weeks. Using paired t-test and 0ne-way ANOVA, it was found out that there is a difference in the effect in lowering hypercholesterolemia (p<0.05). Inducing the albino rats with the two concentrations namely: T4=75% and T5=100% given dosing frequency of once daily and twice a day has no significant difference in lowering the blood cholesterol level. Results suggest that the extract have a potential property in controlling the lipid diet of an individual.

Item Type: Thesis (Other)
Additional Information: BIO 1228 2013
Keywords: 1. Albino rattus norvegicus (albino rats). 2. Rosmarinus officinalis L. (rosemary).
Subjects: Q Science > QH Natural history > QH301 Biology
Q Science > QK Botany
Q Science > QL Zoology
Users: College of Science and Computer Studies > Biological Science
Depositing User: Ivyjoy Viray
Date Deposited: 10 Nov 2015 08:45
Last Modified: 11 Nov 2015 02:05
URI: http://thesis.dlsud.edu.ph/id/eprint/418

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