A comparative study on the toxicity of the different leaf extracts of Nerium indicum (adelfa) and Tinospora umphii (makabuhay) on Rattus sp. (albino rat).

Lao, Niniveh B. and Urbano, Florida R. (1998) A comparative study on the toxicity of the different leaf extracts of Nerium indicum (adelfa) and Tinospora umphii (makabuhay) on Rattus sp. (albino rat). Undergraduate thesis, De La Salle University-Dasmarinas.

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Abstract

Studying the toxicity of a certain plant can lead to a discovery of a much cheaper pesticides. This study tests and compares the toxicity of the leaf extracts of Nerium indicum (Adelfa) and Tinospora rumphii (Makabuhay) on Rattus sp. (Albino rat). The gathering of Makabuhay leaves was done at Bacoor, Cavite and the gathering of Adelfa was at Quezon City. The leaves of Makabuhay and Adelfa were extracted in their specific solvent and rotary evaporator was used for further extraction. The different leaf extracts were administered orally using the gavage method to the thirty-five albino rats of the same age and weight. Mortality rate, time in seconds for death to ensue on rat, and behavioral changes were recorded for each group of rats after the treatment of the leaf extracts. Based on the result of the study, the following conclusions were made: that both extracts of Makabuhay leaves and Adelfa leaves are toxic to albino rats; Adelfa leaf extract with a 100% concentration is more toxic than Makabuhay leaf extract including the other extract concentrations. There was a high significant difference on the effect of the different treatment to the mortality rate of rats.

Item Type: Thesis (Undergraduate)
Additional Information: BIO 342 1998
Subjects: Q Science > QH Natural history > QH301 Biology
Q Science > QK Botany
Q Science > QL Zoology
Users: College of Science and Computer Studies > Biological Science
Depositing User: Ms. Bibiana Alcantara
Date Deposited: 09 Dec 2015 04:29
Last Modified: 09 Dec 2015 04:29
URI: http://thesis.dlsud.edu.ph/id/eprint/327

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